靶标:
SLC22A2
产品别名:
OCT2; SLC22A2; solute carrier family 22 member 2; solute carrier family 22 member 2; solute carrier family 22 member 2; organic cation transporter 2; solute carrier family 22 (organic cation transporter), member 2; 溶质载体家族蛋白22成员A2;
背景信息:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008],