靶标:
SLC22A1
产品别名:
HOCT1; OCT1; oct1_cds; SLC22A1; solute carrier family 22 member 1; solute carrier family 22 member 1; solute carrier family 22 member 1; organic cation transporter 1; solute carrier family 22 (organic cation transporter), member 1; 溶质载体家族蛋白22成员A1; 溶质载体家族蛋白22成员A1/有机阳离子转运蛋白1;
背景信息:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008],