靶标:
SLC8A3
产品别名:
NCX3; SLC8A3; solute carrier family 8 member A3; solute carrier family 8 member A3; sodium/calcium exchanger 3; Na(+)/Ca(2+)-exchange protein 3; sodium/calcium exchanger SLC8A3; solute carrier family 8 (sodium/calcium exchanger), member 3; 钠钙交换蛋白3;
背景信息:
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013],