靶标:
SCG5
产品别名:
7B2; P7B2; SGNE1; SgV; SCG5; secretogranin V; secretogranin V; neuroendocrine protein 7B2; pituitary polypeptide; prohormone convertase chaperone; secretogranin-5; secretory granule endocrine protein I; secretory granule, neuroendocrine protein 1 (7B2 protein); 分泌粒蛋白Ⅴ(SCG5); 神经内分泌颗粒蛋白5;
背景信息:
This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. [provided by RefSeq, Jul 2016],