靶标:
SFRP5
产品别名:
SARP3; SFRP5; secreted frizzled related protein 5; secreted frizzled related protein 5; secreted frizzled-related protein 5; FRP-1b; SARP-3; frizzled-related protein 1b; sFRP-5; secreted apoptosis related protein 3; 分泌凋亡相关蛋白5; 分泌型卷曲相关蛋白5(SFRP5);
背景信息:
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.