靶标:
CX3CL1
产品别名:
ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1; fractalkine; neurotactin; CX3CL1; C-X3-C motif chemokine ligand 1; C-X3-C motif chemokine ligand 1; fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; chemokine (C-X3-C motif) ligand 1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small-inducible cytokine D1; 趋化因子C-X3-C-基元配体1(CX3CL1);
背景信息:
function:The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.,induction:By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells.,online information:CX3CL1 entry,PTM:A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.,similarity:Belongs to the intercrine delta family.,subunit:Monomer.,tissue specificity:Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.,