靶标：
CXCL11
产品别名：
H174； I-TAC； IP-9； IP9； SCYB11； SCYB9B； b-R1； CXCL11； C-X-C motif chemokine ligand 11； C-X-C motif chemokine ligand 11； C-X-C motif chemokine 11； beta-R1； chemokine (C-X-C motif) ligand 11； interferon gamma-inducible protein 9； interferon-inducible T-cell alpha chemoattractant； small inducible cytokine B11； small inducible cytokine subfamily B (Cys-X-Cys), member 11； small inducible cytokine subfamily B (Cys-X-Cys), member 9B； 干扰素诱导T-细胞α亚族趋化剂(ITaC)； 干扰素诱导T细胞趋化因子；
背景信息：
disease:Expressed in a variety of skin disorders, including allergic contact dermatitis, lichen planus and mycosis fungoides.,function:Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.,induction:By interferon gamma and interferon beta. Induction by IFN-gamma is enhanced by TNF-alpha in monocytes, dermal fibroblasts and endothelial cells, and by IL-1 in astrocytes.,mass spectrometry: PubMed:10233762,online information:CXCL11 entry,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,tissue specificity:High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.,
