靶标：
CCL23
产品别名：
CK-BETA-8； CKb8； Ckb-8； Ckb-8-1； MIP-3； MIP3； MPIF-1； SCYA23； hmrp-2a； CCL23； C-C motif chemokine ligand 23； C-C motif chemokine ligand 23； C-C motif chemokine 23； C6 beta-chemokine； chemokine (C-C motif) ligand 23； macrophage inflammatory protein 3； myeloid progenitor inhibitory factor 1； small inducible cytokine subfamily A (Cys-Cys), member 23； 巨噬细胞炎性蛋白；
背景信息：
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013],
