靶标:
CCL17
产品别名:
A-152E5.3; ABCD-2; SCYA17; TARC; CCL17; C-C motif chemokine ligand 17; C-C motif chemokine ligand 17; C-C motif chemokine 17; CC chemokine TARC; T cell-directed CC chemokine; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; small-inducible cytokine A17; thymus and activation-regulated chemokine; 胸腺活化调节趋化因子; 胸腺激活调节趋化因子(TARC);
背景信息:
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],