靶标：
RNH1
产品别名：
RAI； RNH； RNH1； ribonuclease/angiogenin inhibitor 1； ribonuclease/angiogenin inhibitor 1； ribonuclease inhibitor； placental RNase inhibitor； placental ribonuclease inhibitor； testicular tissue protein Li 164； 核糖核酸抑制因子(RI)； 核糖核酸酶抑制因子1；
背景信息：
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010],
