靶标：
RGS1
产品别名：
1R20； BL34； HEL-S-87； IER1； IR20； RGS1； regulator of G protein signaling 1； regulator of G protein signaling 1； regulator of G-protein signaling 1； B-cell activation protein BL34； early response protein 1R20； epididymis secretory protein Li 87； immediate-early response 1, B-cell specific； regulator of G-protein signalling 1； G蛋白信号转导调节因子1； 蛋白信号调节因子1(RGS1)；
背景信息：
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008],
