靶标：
RFC4
产品别名：
A1； RFC37； RFC4； replication factor C subunit 4； replication factor C subunit 4； replication factor C subunit 4； A1 37 kDa subunit； RF-C 37 kDa subunit； RFC 37 kDa subunit； activator 1 37 kDa subunit； activator 1 subunit 4； replication factor C (activator 1) 4, 37kDa； replication factor C 37 kDa subunit；
背景信息：
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
