靶标:
RENBP
产品别名:
RBP; RNBP; RENBP; renin binding protein; renin binding protein; N-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; 晚期糖基化终末产物(AGE); 肾素结合蛋白; 肾素结合蛋白(RENBP);
背景信息:
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.