靶标:
PYGB
产品别名:
GPBB; PYGB; glycogen phosphorylase B; glycogen phosphorylase B; glycogen phosphorylase, brain form; phosphorylase, glycogen; brain; 糖原磷酸化酶B(PYGB); 脑糖原酶;
背景信息:
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.