靶标：
PTH1R
产品别名：
EKNS； PFE； PTHR； PTHR1； PTH1R； parathyroid hormone 1 receptor； parathyroid hormone 1 receptor； parathyroid hormone/parathyroid hormone-related peptide receptor； PTH/PTHr receptor； PTH/PTHrP type I receptor； PTH1 receptor； parathyroid hormone receptor 1； parathyroid hormone/parathyroid hormone-related protein receptor； seven transmembrane helix receptor； 甲状旁腺素受体1(PTHR1)；
背景信息：
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],
