靶标:
PTGDR
产品别名:
AS1; ASRT1; DP; DP1; PTGDR1; PTGDR; prostaglandin D2 receptor; prostaglandin D2 receptor; prostaglandin D2 receptor; PGD2 receptor;
背景信息:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],