靶标：
PSMB4
产品别名：
HN3； HsN3； PRAAS3； PROS-26； PROS26； PSMB4； proteasome 20S subunit beta 4； proteasome 20S subunit beta 4； proteasome subunit beta type-4； 26 kDa prosomal protein； hsBPROS26； macropain beta chain； multicatalytic endopeptidase complex beta chain； proteasome (prosome, macropain) subunit, beta type, 4； proteasome beta chain； proteasome chain 3； proteasome subunit HsN3； proteasome subunit beta 4； proteasome subunit beta7； proteasome subunit, beta type, 4； testis tissue sperm-binding protein Li 79P；
背景信息：
Proteasome subunit beta type-4 also known as 20S proteasome subunit beta-7 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB4 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
