靶标：
PSMB2
产品别名：
HC7-I； PSMB2； proteasome 20S subunit beta 2； proteasome 20S subunit beta 2； proteasome subunit beta type-2； macropain subunit C7-I； multicatalytic endopeptidase complex subunit C7-1； multicatalytic endopeptidase complex subunit C7-I； proteasome (prosome, macropain) subunit, beta type, 2； proteasome beta 2 subunit； proteasome component C7-I； proteasome subunit beta 2； proteasome subunit beta4； proteasome subunit, beta type, 2； testicular tissue protein Li 152；
背景信息：
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
