靶标：
PSMA7
产品别名：
C6； HEL-S-276； HSPC； RC6-1； XAPC7； PSMA7； proteasome 20S subunit alpha 7； proteasome 20S subunit alpha 7； proteasome subunit alpha type-7； epididymis secretory protein Li 276； proteasome (prosome, macropain) subunit, alpha type, 7； proteasome subunit RC6-1； proteasome subunit XAPC7； proteasome subunit alpha 4； proteasome subunit alpha 7； testicular tissue protein Li 151； 蛋白酶体PSMα7； 蛋白酶体亚基α7(PSMa7)；
背景信息：
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9. [provided by RefSeq, Jul 2012],
