靶标：
PPP1R1A
产品别名：
I1； IPP1； PPP1R1A； protein phosphatase 1 regulatory inhibitor subunit 1A； protein phosphatase 1 regulatory inhibitor subunit 1A； protein phosphatase 1 regulatory subunit 1A； I-1； IPP-1； inhibitor-1； protein phosphatase inhibitor-1；
背景信息：
function:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,
