靶标:
PLCL1
产品别名:
PLCE; PLCL; PLDL1; PPP1R127; PRIP; PLCL1; phospholipase C like 1 (inactive); phospholipase C like 1 (inactive); inactive phospholipase C-like protein 1; PLC-L1; phospholipase C, epsilon; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; protein phosphatase 1, regulatory subunit 127; 磷脂酶C1样蛋白; 磷酯酶C样蛋白1(PLCL1);
背景信息:
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.