靶标：
PLCD1
产品别名：
NDNC3； PLC-III； PLCD1； phospholipase C delta 1； phospholipase C delta 1； 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1； PLC-delta-1； Phospholipase C I 1； epididymis secretory sperm binding protein； phosphoinositide phospholipase C-delta-1； phospholipase C-III； 磷酯酶Cδ1(PLCd1)； 磷酸肌醇磷脂酶C；
背景信息：
This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
