靶标：
SERPINA4
产品别名：
KAL； KLST； KST； PI-4； PI4； kallistatin； SERPINA4； serpin family A member 4； serpin family A member 4； kallistatin； kallikrein inhibitor； peptidase inhibitor 4； protease inhibitor 4 (kallistatin)； serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4； serpin A4； serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4； sserpin family A member 4； testicular secretory protein Li 22； 激肽释放酶抑制剂； 激肽释放酶结合蛋白(KAL)；
背景信息：
function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
