靶标：
PI3
产品别名：
ESI； SKALP； WAP3； WFDC14； cementoin； PI3； peptidase inhibitor 3； peptidase inhibitor 3； elafin； PI-3； WAP four-disulfide core domain 14； WAP four-disulfide core domain protein 14； elastase-specific inhibitor； peptidase inhibitor 3, skin-derived； pre-elafin； protease inhibitor 3, skin-derived (SKALP)； protease inhibitor WAP3； skin-derived antileukoproteinase； trappin-2； 弹性蛋白酶抑制剂； 皮肤衍生肽酶抑制因子3(PI3)；
背景信息：
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014],
