靶标：
PDHB
产品别名：
E1beta； PDHBD； PDHE1-B； PDHE1B； PHE1B； PDHB； pyruvate dehydrogenase E1 subunit beta； pyruvate dehydrogenase E1 subunit beta； pyruvate dehydrogenase E1 component subunit beta, mitochondrial； epididymis secretory sperm binding protein； pyruvate dehydrogenase (lipoamide) beta； pyruvate dehydrogenase E1 beta subunit； pyruvate dehydrogenase, E1 beta polypeptide； 丙酮酸脱氢酶E1β亚单位； 丙酮酸脱氢酶E1β亚基； 丙酮酸脱氢酶β(PDHb)；
背景信息：
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012],
