靶标:
PDHA2
产品别名:
PDHAL; SPGF70; PDHA2; pyruvate dehydrogenase E1 subunit alpha 2; pyruvate dehydrogenase E1 subunit alpha 2; pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; PDHE1-A type II; pyruvate dehydrogenase (lipoamide) alpha 2; pyruvate dehydrogenase E1 alpha 2 subunit; pyruvate dehydrogenase alpha 2; pyruvate dehydrogenase, E1-alpha polypeptide, testis specific; PDHA2蛋白;
背景信息:
catalytic activity:Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2).,cofactor:Thiamine pyrophosphate.,enzyme regulation:E1 activity is regulated by phosphorylation (inactivation) and dephosphorylation (activation) of the alpha subunit.,function:The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).,subunit:Tetramer of 2 alpha and 2 beta subunits.,tissue specificity:Testis. Expressed in postmeiotic spermatogenic cells.,