靶标:
PDE4A
产品别名:
DPDE2; PDE4; PDE46; PDE4A; phosphodiesterase 4A; phosphodiesterase 4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4; 磷酸二酯酶4A; 磷酸二酯酶4A8;
背景信息:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.