靶标:
P2RY6
产品别名:
P2Y6; P2RY6; pyrimidinergic receptor P2Y6; pyrimidinergic receptor P2Y6; P2Y purinoceptor 6; G-coupled nucleotide receptor; P2 purinoceptor; P2Y6 receptor; pyrimidinergic receptor P2Y, G-protein coupled, 6; G蛋白偶联嘌呤受体p2y6;
背景信息:
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013],