靶标:
P2RX3
产品别名:
P2X3; P2RX3; purinergic receptor P2X 3; purinergic receptor P2X 3; P2X purinoceptor 3; ATP receptor; P2X receptor, subunit 3; purinergic receptor P2X, ligand gated ion channel, 3; purinergic receptor P2X3; purinoceptor P2X3; 三磷酸腺苷受体受体P2X3;
背景信息:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],