靶标：
TNFRSF11B
产品别名：
OCIF； OPG； PDB5； TR1； TNFRSF11B； TNF receptor superfamily member 11b； TNF receptor superfamily member 11b； tumor necrosis factor receptor superfamily member 11B； osteoclastogenesis inhibitory factor； osteoprotegerin； tumor necrosis factor receptor superfamily, member 11b； 骨保护素(OPG)； 骨保护蛋白/护骨素；
背景信息：
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
