靶标：
NPR2
产品别名：
AMD1； AMDM； ANPRB； ANPb； ECDM； GC-B； GCB； GUC2B； GUCY2B； NPRB； NPRBi； SNSK； NPR2； natriuretic peptide receptor 2； natriuretic peptide receptor 2； atrial natriuretic peptide receptor 2； atrial natriuretic peptide B-type receptor； atrial natriuretic peptide receptor type B； guanylate cyclase 2B； guanylate cyclase B； guanylyl cyclase B； natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)； 利钠肽受体B； 钠尿肽受体2(NPR2)；
背景信息：
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008],
