靶标：
PNP
产品别名：
NP； PRO1837； PUNP； PNP； purine nucleoside phosphorylase； purine nucleoside phosphorylase； purine nucleoside phosphorylase； HEL-S-156an； epididymis secretory sperm binding protein Li 156an； inosine phosphorylase； inosine-guanosine phosphorylase； purine-nucleoside:orthophosphate ribosyltransferase； 嘌呤核苷磷酸化酶(PNP)； 嘌呤核苷酶；
背景信息：
The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
