靶标:
NHLH1
产品别名:
HEN1; NSCL; NSCL1; bHLHa35; NHLH1; nescient helix-loop-helix 1; nescient helix-loop-helix 1; helix-loop-helix protein 1; HEN-1; NSCL-1; class A basic helix-loop-helix protein 35; 环一螺旋蛋白1; 螺旋环螺旋蛋白1+2;
背景信息:
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002],