靶标:
NEK2
产品别名:
HsPK21; NEK2A; NLK1; PPP1R111; RP67; NEK2; NIMA related kinase 2; NIMA related kinase 2; serine/threonine-protein kinase Nek2; NIMA (never in mitosis gene a)-related kinase 2; nimA-like protein kinase 1; nimA-related protein kinase 2; protein phosphatase 1, regulatory subunit 111; 中心体相关蛋白激酶Nek2; 永离有丝分裂基因A相关激酶2(NEK2);
背景信息:
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011],