靶标：
DRG1
产品别名：
NEDD3； DRG1； developmentally regulated GTP binding protein 1； developmentally regulated GTP binding protein 1； developmentally-regulated GTP-binding protein 1； DRG-1； NEDD-3； TRAFAC GTPase DRG1； neural precursor cell expressed developmentally down-regulated protein 3； neural precursor cell expressed, developmentally down-regulated 3； translation factor GTPase DRG1； GTP发育调控结合蛋白1；
背景信息：
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.
