靶标：
NDUFA1
产品别名：
CI-MWFE； MC1DN12； MWFE； ZNF183； NDUFA1； NADH:ubiquinone oxidoreductase subunit A1； NADH:ubiquinone oxidoreductase subunit A1； NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1； NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa； NADH-ubiquinone oxidoreductase MWFE subunit； NADH:ubiquinone oxidoreductase (complex 1)； complex I MWFE subunit； type I dehydrogenase； NADH氧化还原酶辅酶1；
背景信息：
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],
