靶标:
MYH2
产品别名:
IBM3; MYH2A; MYHSA2; MYHas8; MYPOP; MyHC-2A; MyHC-IIa; MYH2; myosin heavy chain 2; myosin heavy chain 2; myosin-2; fast 2a myosin heavy chain; inclusion body myopathy 3, autosomal dominant; myosin heavy chain 2a; myosin heavy chain IIa; myosin heavy chain, skeletal muscle, adult 2; myosin, heavy chain 2, skeletal muscle, adult; myosin, heavy polypeptide 2, skeletal muscle, adult; type IIA myosin heavy chain; 肌球蛋白2; 肌球蛋白重链2(MYH2);
背景信息:
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009],