靶标：
MVD
产品别名：
FP17780； MDDase； MPD； POROK7； MVD； mevalonate diphosphate decarboxylase； mevalonate diphosphate decarboxylase； diphosphomevalonate decarboxylase； mevalonate (diphospho) decarboxylase； mevalonate pyrophosphate decarboxylase； 甲羟戊酸脱羧酶；
背景信息：
The enzyme mevalonate pyrophosphate decarboxylase (MVD; EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVDsequence.
