靶标:
MMP16
产品别名:
C8orf57; MMP-X2; MT-MMP2; MT-MMP3; MT3-MMP; MMP16; matrix metallopeptidase 16; matrix metallopeptidase 16; matrix metalloproteinase-16; MMP-16; MT-MMP 3; MT3MMP; MTMMP3; Putative transmembrane protein C8orf57; matrix metallopeptidase 16 (membrane-inserted); membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase; 基质金属蛋白酶-16; 基质金属蛋白酶16(MMP16);
背景信息:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010],