靶标:
MAP3K10
产品别名:
MEKK10; MLK2; MST; MAP3K10; mitogen-activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 10; MKN28 derived nonreceptor_type serine/threonine kinase; MKN28 kinase; mixed lineage kinase 2; protein kinase MST; 丝裂原活化蛋白激酶3K10; 丝裂原活化蛋白激酶激酶激酶10;
背景信息:
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008],