靶标:
MFGE8
产品别名:
BA46; EDIL1; HMFG; HsT19888; MFG-E8; MFGM; OAcGD3S; SED1; SPAG10; hP47; MFGE8; milk fat globule EGF and factor V/VIII domain containing; milk fat globule EGF and factor V/VIII domain containing; lactadherin; O-acetyl disialoganglioside synthase; breast epithelial antigen BA46; medin; milk fat globule-EGF factor 8 protein; sperm associated antigen 10; sperm surface protein hP47; 乳脂球表皮生长因子8(MFGE8); 乳腺上皮细胞抗原BA46;
背景信息:
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],