靶标:
MC2R
产品别名:
ACTHR; MC2R; melanocortin 2 receptor; melanocortin 2 receptor; adrenocorticotropic hormone receptor; ACTH receptor; MC2 receptor; adrenocorticotropin receptor; corticotropin receptor; melanocortin 2 receptor (adrenocorticotropic hormone); 促肾上腺皮质激素受体; 促肾上腺皮质激素受体(ACTHR);
背景信息:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014],