靶标:
MAZ
产品别名:
PUR1; Pur-1; SAF-1; SAF-2; SAF-3; ZF87; ZNF801; Zif87; MAZ; MYC associated zinc finger protein; MYC associated zinc finger protein; myc-associated zinc finger protein; MAZI; purine-binding transcription factor; serum amyloid A activating factor 1; serum amyloid A activating factor 2; transcription factor Zif87; zinc finger protein 801; zinc-finger protein, 87 kilodaltons; 锌指蛋白801;
背景信息:
function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,