靶标:
MAGOH
产品别名:
MAGOH1; MAGOHA; MAGOH; mago homolog, exon junction complex subunit; mago homolog, exon junction complex subunit; protein mago nashi homolog; mago homolog, exon junction complex core component; mago-nashi homolog, proliferation-associated; 增殖相关蛋白MAGOH;
背景信息:
Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts.