靶标：
LIG1
产品别名：
IMD96； LIGI； hLig1； LIG1； DNA ligase 1； DNA ligase 1； DNA ligase 1； ligase I, DNA, ATP-dependent； polydeoxyribonucleotide synthase [ATP] 1； ATP依赖性DNA连接酶Ⅰ(LIG1)； DNA连接酶1；
背景信息：
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
