靶标：
KRT81
产品别名：
HB1； Hb-1； K81； KRTHB1； MLN137； ghHkb1； hHAKB2-1； KRT81； keratin 81； keratin 81； keratin, type II cuticular Hb1； hair keratin K2.9； hard keratin, type II, 1； keratin 81, type II； keratin, hair, basic, 1； metastatic lymph node 137 gene protein； type II hair keratin Hb1； type-II keratin Kb21； 细胞角蛋白81； 角蛋白81(KRT81)；
背景信息：
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008],
