靶标:
KRT2
产品别名:
CK-2e; K2e; KRT2A; KRT2E; KRTE; KRT2; keratin 2; keratin 2; keratin, type II cytoskeletal 2 epidermal; cytokeratin-2e; epithelial keratin-2e; keratin 2, type II; keratin-2 epidermis; keratin-2e; type-II keratin Kb2; 细胞角蛋白2e; 角蛋白2(CK2);
背景信息:
keratin 2(KRT2) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],