靶标:
KLRD1
产品别名:
CD94; KLRD1; killer cell lectin like receptor D1; killer cell lectin like receptor D1; natural killer cells antigen CD94; CD94 antigen; KP43; NK cell receptor; killer cell lectin-like receptor subfamily D, member 1; NK细胞表面抑制性受体CD94; 杀伤细胞凝集素样受体亚家族D成员1(KLRD1);
背景信息:
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],