靶标：
KIR3DL2
产品别名：
3DL2； CD158K； KIR-3DL2； NKAT-4； NKAT4； NKAT4B； p140； KIR3DL2； killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2； killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2； killer cell immunoglobulin-like receptor 3DL2； CD158 antigen-like family member K； KIR antigen 3DL2； MHC class I NK cell receptor； killer Ig receptor； killer cell immunoglobulin-like receptor 2DL2； killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2； killer-cell immunoglobulin-like receptor； natural killer-associated transcript 4； p70 NK receptor CL-5； p70 killer cell inhibitory receptor； p70 natural killer cell receptor clone CL-5； 杀伤细胞免疫球蛋白样受体3DL2(KIR3DL2)；
背景信息：
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2(KIR3DL2) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
