靶标:
ITIH1
产品别名:
H1P; IATIH; IGHEP1; ITI-HC1; ITIH; SHAP; ITIH1; inter-alpha-trypsin inhibitor heavy chain 1; inter-alpha-trypsin inhibitor heavy chain 1; inter-alpha-trypsin inhibitor heavy chain H1; ITI heavy chain H1; inter-alpha (globulin) inhibitor, H1 polypeptide; inter-alpha-inhibitor heavy chain 1; inter-alpha-trypsin inhibitor complex component III; serum-derived hyaluronan-associated protein; 中间α-球蛋白抑制因子H1(ITIH1); 衍生透明质酸相关蛋白;
背景信息:
This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015],